Ithaca College has one of Division III's strongest overall athletic programs. Ithaca finished 22nd in the Directors' Cup standings in 2009-10. The Bombers have won a total of 15 national titles in seven team sports (only one Division III school has won titles in more sports) and five individual sports. Ithaca has ranked in the top 30 of the Directors' Cup standings every year since the program's inception and is one of only nine schools to rank that high each year.

Ithaca teams have won three national championships in football and wrestling, two each in baseball, women's crew and women's soccer, and one each in field hockey, gymnastics and softball. Bomber teams have also produced individual national champions in gymnastics, men's and women's swimming, wrestling, and track and field. Ithaca is sponsoring
26 varsity sports during the 2009-10 school year - 14 for women and 12 for men.

Ithaca is a member of the Eastern College Athletic Conference (ECAC), National Collegiate Gymnastics Association (NCGA), Empire Collegiate Wrestling Conference (ECWC) and the Empire 8. A year ago, Bomber teams were a combined 256-112-5 (.693); 12 were represented in the NCAA playoffs and 12 won Empire 8 tournament and/or regular-season championships. Ithaca won the Empire 8 Commissioner's Cup for the 10th year in a row.

A total of 31 Ithaca student-athletes earned all-American recognition and three were named academic all-American.